[Initial analysis of the use of the L-D-Hydro (Eato L-D-Hydro) organic tubular graft for performing the modified Blalock-Taussig procedure in congenital heart diseases with decreased pulmonary blood flow]

Arq Bras Cardiol. 2005 Mar;84(3):233-6. doi: 10.1590/s0066-782x2005000300007. Epub 2005 Apr 15.
[Article in Portuguese]

Abstract

Objective: To analyze the initial results of the use of an organic tubular graft for systemic-pulmonary anastomoses.

Methods: From March 2002 to April 2003, 10 patients underwent systemic-pulmonary shunt of the modified Blalock-Taussig type, using a new type of biological graft originating from the bovine mesenteric artery treated with polyglycol, the so-called L-D-Hydro. The patients' ages ranged from 3 days to 7 years, and 60% of them were of the male sex. The diagnoses of heart disease were determined on echocardiography. All patients had clinical signs of severe hypoxia (cyanosis). The heart diseases were as follows: tetralogy of Fallot (40%), tricuspid atresia (50%), and atrioventricular septal defect (10%).

Results: One patient died due to sepsis and 9 had an immediate improvement in O2 saturation on pulse oximetry and in the partial oxygen pressure on arterial blood gas analysis. The intensive care unit length of stay ranged from 2 to 6 days. No patient had obstruction of the shunt on the immediate postoperative period or any other complication. All patients had a patent shunt on the echocardiographic studies performed in the immediate postoperative period and later, in the third postoperative month. No bleeding occurred during surgery or in the postoperative period.

Conclusion: The tubular L-D-Hydro graft proved to be promising for performing systemic-pulmonary shunt as an alternative for the inorganic products available in the market, however, we need a greater number of implantations and late follow-up for definitive assessment.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Arteriovenous Shunt, Surgical*
  • Biocompatible Materials*
  • Blood Vessel Prosthesis*
  • Cattle
  • Child
  • Child, Preschool
  • Female
  • Heart Defects, Congenital / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mesenteric Arteries
  • Pulmonary Artery / physiology
  • Pulmonary Artery / surgery*
  • Regional Blood Flow
  • Subclavian Artery / surgery*

Substances

  • Biocompatible Materials