ATM: HIV-1's Achilles heel?

Nat Cell Biol. 2005 May;7(5):452-3. doi: 10.1038/ncb0505-452.
No abstract available

Publication types

  • News
  • Comment

MeSH terms

  • Ataxia Telangiectasia Mutated Proteins
  • Cell Cycle Proteins / antagonists & inhibitors
  • Cell Cycle Proteins / metabolism
  • Cell Death / drug effects
  • Cell Death / physiology
  • Cells, Cultured
  • DNA Repair / drug effects
  • DNA Repair / physiology
  • DNA-Binding Proteins / antagonists & inhibitors
  • DNA-Binding Proteins / metabolism
  • HIV Infections / drug therapy
  • HIV Infections / virology*
  • HIV Protease Inhibitors / pharmacology
  • HIV-1 / drug effects
  • HIV-1 / physiology*
  • Humans
  • Morpholines / pharmacology
  • Protein Serine-Threonine Kinases / antagonists & inhibitors
  • Protein Serine-Threonine Kinases / metabolism
  • Pyrones / pharmacology
  • Tumor Suppressor Proteins / antagonists & inhibitors
  • Tumor Suppressor Proteins / metabolism
  • Virus Replication / drug effects
  • Virus Replication / physiology*

Substances

  • 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one
  • Cell Cycle Proteins
  • DNA-Binding Proteins
  • HIV Protease Inhibitors
  • Morpholines
  • Pyrones
  • Tumor Suppressor Proteins
  • ATM protein, human
  • Ataxia Telangiectasia Mutated Proteins
  • Protein Serine-Threonine Kinases