With respect to the water cycling, the natural reproducible ability of water resource (NRAWR) was expressed, and the spatial and temporal differences of NRAWR in the northeast part of China were anatomized systematically with the GIS techniques. Furthermore, the response of NRAWR in the northeast part of China to land use changes was described based on land use patterns of the northeast part of China in 1986,1996 and 2000. Water resource in the northeast part of China has the distinct spatial and temporal variation during the period from 1956 to 2001 with the multi-year volume of 199.152 billion m(3), and the temporal change of NRAWR has 33-year, 11-year and 4-year cycles. In the phase from 1980 to 2001, the NRAWR in the northeast part of China has the descending trend, and the yearly variation range and intensity have marked spatial evolutional features. The coupling change of NRAWR and land use change shows that, in order to maintaining an higher NRAWR level under the condition of the acute anthropic interferes in the northeast part of China, the land use pattern should be adjusted based on the distributed eco-hydrological mechanism.