Multidetector computed tomography (MDCT) possesses distinct advantages for examination of the kidneys. It carries the potential of becoming the gold standard of diagnostic work-up and surgical planning for most renal diseases and replacing conventional methods such as i.v. urography and angiography. The most outstanding improvements, in comparison to single slice spiral CT, are the speedier image acquisition and enhanced z-axis resolution, which aids particularly in visualization of the urinary tract as it aligns along the axis of the body. Respiratory artifacts are few or nonexistent even in patients who cannot hold their breath. This overview presents a strategy for prudent management of MDCT examinations and describes examination of the most important and frequent renal diseases using MDCT.