On January 6, 2005, the National Response Plan (NRP) was introduced to standardize a national approach for responding to natural or man-made threats. The underlying structure for the NRP is the National Incident Management System, which establishes standardized training, organization, and communications procedures that can be used by multiple jurisdictions to interact in a disaster. The NRP clearly identifies authority and leadership responsibilities. The NRP organizes the government's emergency operations into 15 emergency support functions, of which Emergency Support Function #8 pertains to public health and medical services. The United States Public Health Service (PHS) Commissioned Corps is one of the seven uniformed services of the United States, and PHS officers can be deployed to help meet urgent public health needs when traditional mechanisms and resources are overwhelmed. The role of PHS nurses is presented.