Two new human cases of dirofilariasis, both due to Dirofilaria (Nochtiella) repens, recently occurring in Nuoro province (Sardinia) on people permanently resident in the island, are described. The parasite was located in one case into the uterine round ligament, in the other it was subconjunctival. Some observations about the diagnostic difficulties in the first one and the dramatic symptoms in the second, whose parasite was yet alive during the surgical ablaction, are discussed. These cases are the 9th and the 10th, respectively, reported in man in Sardinia, but it is possible that other cases are undiagnosed and consequently are not published.