Objective: To report the first birth after transfer of cryopreserved embryos generated by intracytoplasmic sperm injection of cryopreserved testicular spermatozoa into cryopreserved human oocytes.
Design: Case report.
Setting: Tertiary center for reproductive technology.
Patient(s): A 36-year-old woman with primary infertility of 3 years' duration and a 37-year-old man with congenital bilateral absence of the vas deferens.
Intervention(s): Cryopreservation of human embryos after oocytes and sperm thawing.
Main outcome measure(s): Live birth.
Result(s): A healthy, normal female infant with a birth weight of 2,950 g was born by cesarean section at 38 weeks' gestation, with normal 6-month follow-up.
Conclusion(s): Embryo cryopreservation can lead to successful results, even with the use of cryopreserved gametes.