HDBStat!: a platform-independent software suite for statistical analysis of high dimensional biology data

BMC Bioinformatics. 2005 Apr 6:6:86. doi: 10.1186/1471-2105-6-86.

Abstract

Background: Many efforts in microarray data analysis are focused on providing tools and methods for the qualitative analysis of microarray data. HDBStat! (High-Dimensional Biology-Statistics) is a software package designed for analysis of high dimensional biology data such as microarray data. It was initially developed for the analysis of microarray gene expression data, but it can also be used for some applications in proteomics and other aspects of genomics. HDBStat! provides statisticians and biologists a flexible and easy-to-use interface to analyze complex microarray data using a variety of methods for data preprocessing, quality control analysis and hypothesis testing.

Results: Results generated from data preprocessing methods, quality control analysis and hypothesis testing methods are output in the form of Excel CSV tables, graphs and an Html report summarizing data analysis.

Conclusion: HDBStat! is a platform-independent software that is freely available to academic institutions and non-profit organizations. It can be downloaded from our website http://www.soph.uab.edu/ssg_content.asp?id=1164.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Biology / methods*
  • Computational Biology / instrumentation*
  • Computational Biology / methods*
  • Computer Graphics
  • Computers
  • Data Interpretation, Statistical
  • Database Management Systems
  • Gene Expression Profiling
  • Genomics / methods
  • Internet
  • Models, Statistical
  • Oligonucleotide Array Sequence Analysis
  • Programming Languages
  • Proteomics / methods
  • Quality Control
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Software Design
  • Software*
  • User-Computer Interface