[Induction chemotherapy in the treatment of head and neck cancer in advanced stages]

Abstract

Fifty patients with inoperable head and neck carcinomas were treated with Cisplatin-5-fluorouracil induction chemotherapy. After 3 years follow-up, characteristics of patients have been studied, that is: age, sex, stage, primary site, histological type, histological grade and performance status. The analysis of chemotherapy treatment and results on primary tumor and lymphatic areas are presented. A total response rate of 83.3% with 22.9% of complete response rate have been observed. Local treatment after chemotherapy is studied. Radiotherapy increased response in 33.4% of cases. Response duration and survival is to have a complete response after systemic and local treatment. Literature is revised.