Abstract
This study aimed to identify and to evaluate the level of potency fluctuations of the pertussis component of Polish-produced DTP vaccine lots produced within 1972-2001 due to the changes having occurred in production and potency testing procedures. Obtained results showed high consistency of the production and control tests confirming relevant quality of country-produced DTP vaccine.
MeSH terms
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Animals
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Antibody Formation
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Antigens, Bacterial
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Bordetella pertussis / immunology
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Diphtheria-Tetanus-Pertussis Vaccine / immunology*
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Diphtheria-Tetanus-Pertussis Vaccine / standards*
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Dose-Response Relationship, Immunologic
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Humans
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Incidence
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Poland / epidemiology
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Reproducibility of Results
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Retrospective Studies
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Time Factors
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Whooping Cough / epidemiology*
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Whooping Cough / immunology*
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Whooping Cough / prevention & control
Substances
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Antigens, Bacterial
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Diphtheria-Tetanus-Pertussis Vaccine