Norditerpene and diterpene alkaloids from Aconitum variegatum

Jesús G Díaz; Juan García Ruiza; Werner Herz

doi:10.1016/j.phytochem.2005.01.019

Norditerpene and diterpene alkaloids from Aconitum variegatum

Phytochemistry. 2005 Apr;66(7):837-46. doi: 10.1016/j.phytochem.2005.01.019.

Authors

Jesús G Díaz¹, Juan García Ruiza, Werner Herz

Affiliation

¹ Instituto de Bio-Orgánica A. González, Universidad de La Laguna, Ctra a la Esperanza 2, 38206 La Laguna, Tenerife, Spain.

PMID: 15797610
DOI: 10.1016/j.phytochem.2005.01.019

Abstract

Aerial parts of Aconitum variegatum L. from the Pyrenees furnished four norditerpene alkaloids, 16 beta-hydroxycardiopetaline, 8-ethoxysachaconitine, 14-acetylgenicunine B, N-deethyl-N-19-didehydrosachaconitine, five diterpene alkaloids 15-veratroyldictizine, 15-veratroyl-17-acetyldictizine, 15-veratroyl-17-acetyl-19-oxodictizine, N-ethyl-1 alpha-hydroxy-17-veratroyldictizine, variegatine and the known alkaloids sachaconitine, 14-O-acetylsachaconitine, karakoline, talatizamine, 10-hydroxytalatizamine, 14-acetyltalatizamine, 14-acetyl-10-hydroxytalatizamine, N-methylarmepavine, pengshenin B, delsoline, dihydrodelsoline, delcosine and genicunin B. Structures of the alkaloids were established by MS, 1D- and 2D-NMR techniques.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aconitum / chemistry*
Alkaloids / chemistry
Alkaloids / isolation & purification*
Diterpenes / chemistry
Diterpenes / isolation & purification*
Molecular Structure

Substances

Alkaloids
Diterpenes