In this paper the most relevant findings of our research team on pathological gambling in the last decade are presented. There is no conclusive empirical evidence of a specific profile of the pathological gamblers. The choice treatment appears to be stimulus control and in vivo exposure with response prevention, followed by a cognitive-behavioral intervention in relapse prevention. Predictive variables for the therapeutic failure were the dissatisfaction with the treatment, the alcohol abuse and the neuroticism as a personality variable. Unanswered questions for future research in this field are commented upon.