Design and synthesis of a neutral fluorescent macrocyclic receptor for the recognition of urea in chloroform

Org Lett. 2005 Mar 31;7(7):1283-5. doi: 10.1021/ol050034h.

Abstract

[structure: see text] An artificial macrocyclic fluorescent receptor 1 has been designed and synthesized for the recognition of urea. 1 shows significant fluorescence quenching on complexation with urea and thiourea in chloroform and thus may be used as a synthetic fluorescent molecular sensor for their determination in a nondegradative way.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Chloroform / chemistry*
  • Fluorescent Dyes / chemical synthesis*
  • Fluorescent Dyes / chemistry
  • Molecular Conformation
  • Molecular Structure
  • Spectrometry, Fluorescence
  • Urea / analysis*
  • Urea / chemistry

Substances

  • Fluorescent Dyes
  • Chloroform
  • Urea