Cytotoxic xanthones from Cudrania tricuspidata

Byong Won Lee; Sang Wan Gal; Ki-Min Park; Ki Hun Park

doi:10.1021/np030481a

Cytotoxic xanthones from Cudrania tricuspidata

J Nat Prod. 2005 Mar;68(3):456-8. doi: 10.1021/np030481a.

Authors

Byong Won Lee¹, Sang Wan Gal, Ki-Min Park, Ki Hun Park

Affiliation

¹ Department of Agricultural Chemistry, Division of Applied Life Science (BK21 program), The Research Institute of Natural Science, Gyeongsang National University, RAIRC, Jinju 660-701, Korea.

PMID: 15787460
DOI: 10.1021/np030481a

Abstract

The new isoprenylated tetrahydroxyxanthone, 2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen-9-one (1), was isolated from the root bark of Cudrania tricuspidata together with macluraxanthone B (2) and cudraxanthone L (3), which were fully characterized by NMR spectroscopic and X-ray crystallographic analyses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / isolation & purification*
Antineoplastic Agents, Phytogenic / pharmacology
Crystallography, X-Ray
Drug Screening Assays, Antitumor
Humans
Korea
Molecular Conformation
Molecular Structure
Moraceae / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Plant Bark / chemistry
Plants, Medicinal / chemistry*
Tumor Cells, Cultured
Xanthones / chemistry
Xanthones / isolation & purification*
Xanthones / pharmacology

Substances

2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen-9-one
Antineoplastic Agents, Phytogenic
Xanthones
cudraxanthone L
macluraxanthone B