Brucellosis: haemorrhagic pleural effusion

Med Princ Pract. 2005 Mar-Apr;14(2):118-20. doi: 10.1159/000083924.

Abstract

Objectives: To describe haemorrhagic pleural effusion as a rare complication of brucellosis that finally needed lung decortication.

Clinical presentation and intervention: A 37-year-old female presented with a 1-week history of fever, dry cough and pleuritic chest pain. Physical examination showed signs of right pleural effusion and hepatosplenomegaly. Complete blood count showed pancytopenia, white blood cells 2.9/mm3, haemoglobin 10 g/dl, platelets 131/mm3. Chest X-ray confirmed a moderate right pleural effusion, that was found to be exudative biochemically. Culture of pleural fluid and blood grew Brucella species. Fever subsided with Brucella chemotherapy, but pleural effusion persisted. Computed tomographic (CT) chest scan showed a large loculated pleural effusion, which failed to resolve despite repeated aspirations under CT guidance. Fluid was always found to be haemorrhagic. Finally, lung decortication was done with successful outcome.

Conclusion: This case showed that brucellosis can cause haemorrhagic pleural effusion that needs lung decortication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brucellosis / complications
  • Brucellosis / diagnosis*
  • Brucellosis / drug therapy
  • Doxycycline / administration & dosage
  • Doxycycline / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Hemorrhage / complications
  • Hemorrhage / diagnosis*
  • Hemorrhage / surgery
  • Humans
  • Lung / physiopathology*
  • Lung / surgery
  • Pleural Effusion / complications
  • Pleural Effusion / diagnosis*
  • Pleural Effusion / surgery
  • Saudi Arabia
  • Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Doxycycline