Physiologic consequences of acute renal failure on the critically ill

Eric A J Hoste; Jan J De Waele

doi:10.1016/j.ccc.2005.01.003

Physiologic consequences of acute renal failure on the critically ill

Crit Care Clin. 2005 Apr;21(2):251-60. doi: 10.1016/j.ccc.2005.01.003.

Authors

Eric A J Hoste¹, Jan J De Waele

Affiliation

¹ Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium. eric.hoste@ugent.be

PMID: 15781161
DOI: 10.1016/j.ccc.2005.01.003

Abstract

Acute renal failure (ACF) causes increased levels of uremic retention products, acidosis, and volume overload. These factors contribute to a dysregulated inflammatory response and decreased immunity, and interfere with normal function of many organs. ACF may play an important role in the etiology of multiple organ dysfunction.

Publication types

Review

MeSH terms

Acidosis / physiopathology
Acute Kidney Injury / complications
Acute Kidney Injury / physiopathology*
Humans
Inflammation / physiopathology
Multiple Organ Failure / etiology
Shock / etiology
Uremia / physiopathology
Water-Electrolyte Imbalance / physiopathology