Renal cell-to-cell communication via extracellular ATP

Physiology (Bethesda). 2005 Apr:20:86-90. doi: 10.1152/physiol.00002.2005.

Abstract

In the kidney, macula densa cells communicate with the mesangial cell-afferent arteriolar smooth muscle cell complex through ATP signaling. This signaling process involves release of ATP across the macula densa basolateral membrane through a maxi anion channel and the interaction of ATP with purinergic P2 receptors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Animals
  • Cell Communication / physiology*
  • Extracellular Space / metabolism
  • Humans
  • Kidney / cytology*
  • Kidney / physiology*

Substances

  • Adenosine Triphosphate