2-Deoxystreptamine: central scaffold of aminoglycoside antibiotics

Chem Rev. 2005 Mar;105(3):775-91. doi: 10.1021/cr0404085.

Authors

Guuske F Busscher¹, Floris P J T Rutjes, Floris L van Delft

Affiliation

¹ IMM Organic Chemistry, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.

PMID: 15755076
DOI: 10.1021/cr0404085

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Aminoglycosides / biosynthesis
Aminoglycosides / chemistry
Aminoglycosides / pharmacology*
Anti-Bacterial Agents / biosynthesis
Anti-Bacterial Agents / chemical synthesis
Anti-Bacterial Agents / pharmacology*
Bacteria / classification
Bacteria / drug effects*
Drug Design
Hexosamines / biosynthesis
Hexosamines / chemical synthesis
Hexosamines / chemistry*
Hexosamines / pharmacology*
Structure-Activity Relationship

Substances

Aminoglycosides
Anti-Bacterial Agents
Hexosamines
2-deoxystreptamine