Asymmetric alkylation of dimethoxyphosphoryl-N-[1-(S)-alpha-methylbenzyl]acetamide enolates. Synthesis of both stereoisomers from the same source of chirality by changing the equivalents of LDA

Chem Commun (Camb). 2005 Mar 14:(10):1336-8. doi: 10.1039/b416616g. Epub 2005 Jan 18.

Abstract

A new methodology has been developed for the synthesis of both stereoisomers from a single chiral source.