During our exploration on the history of compilation, spread, reprinting of Yong le da dian (Great Canon of Yongle) and the analysis made on the materials of medicine; history of medicine, and medical literature in the "17th Volume of Great Canon of Yongle Newly Discovered Overseas", we found that there are materials cited over 10 kinds of literature of the Song, Jin, and Yuan dynasties and other fragmentary materials. The academic value of the materials include; for the proofreading and collation of available extant medical literature; for the supplement of lost medical books or remained medical books; for the exploration of new medical historical materials; and for the correction of errors in modern tool books in TCM.