Rhizochalin A, a novel two-headed sphingolipid from the sponge Rhizochalina incrustata

J Nat Prod. 2005 Feb;68(2):255-7. doi: 10.1021/np049710z.

Abstract

Rhizochalin A (4), the fourth representative of two-headed glycosphingolipids, was isolated as its peracetate from the sponge Rhizochalina incrustata. Its structure has been established as the 2-ethyl carbamoate of rhizochalin on the basis of spectroscopic data and chemical transformations.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Candida glabrata / drug effects
  • Glycolipids / chemistry
  • Glycolipids / pharmacology
  • Glycosphingolipids / chemistry
  • Glycosphingolipids / isolation & purification*
  • Glycosphingolipids / pharmacology
  • Mice
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera / chemistry*
  • Russia
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Antineoplastic Agents
  • Glycolipids
  • Glycosphingolipids
  • oceanapiside
  • rhizochalin A