Promotion of oxygen atom transfer in Mo and W enzymes by bicyclic forms of the pterin cofactor

Chem Commun (Camb). 2005 Jan 14:(2):177-9. doi: 10.1039/b415480k. Epub 2004 Dec 2.

Abstract

Density functional theory calculations suggest that bicyclic structures of the "molybdopterin" in DMSO reductases may have an important catalytic role in oxygen atom transfer reactions.

MeSH terms

  • Coenzymes / chemistry*
  • Coenzymes / metabolism
  • Enzymes / chemistry*
  • Enzymes / metabolism*
  • Molecular Structure
  • Molybdenum / metabolism*
  • Oxygen / chemistry*
  • Oxygen / metabolism
  • Pterins / chemistry*
  • Pterins / metabolism
  • Tungsten / metabolism*

Substances

  • Coenzymes
  • Enzymes
  • Pterins
  • Molybdenum
  • Oxygen
  • Tungsten