Abstract
To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importance and significant contents of reference which have been consulted in the past twenty years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Antineoplastic Agents, Alkylating / pharmacology
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Antispermatogenic Agents / pharmacology
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Diterpenes / chemical synthesis
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Diterpenes / isolation & purification
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Diterpenes / pharmacology*
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Diterpenes / toxicity
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Epoxy Compounds
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Humans
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Immunosuppressive Agents / pharmacology*
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Phenanthrenes / isolation & purification
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Phenanthrenes / pharmacology*
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Phenanthrenes / toxicity
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Tripterygium* / chemistry
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Antineoplastic Agents, Alkylating
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Antispermatogenic Agents
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Diterpenes
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Epoxy Compounds
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Immunosuppressive Agents
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Phenanthrenes
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triptolide
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triptophenolide