[Progress in research on triptolide]

Zhongguo Zhong Yao Za Zhi. 2005 Feb;30(3):170-4.
[Article in Chinese]

Abstract

To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importance and significant contents of reference which have been consulted in the past twenty years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Antineoplastic Agents, Alkylating / pharmacology
  • Antispermatogenic Agents / pharmacology
  • Diterpenes / chemical synthesis
  • Diterpenes / isolation & purification
  • Diterpenes / pharmacology*
  • Diterpenes / toxicity
  • Epoxy Compounds
  • Humans
  • Immunosuppressive Agents / pharmacology*
  • Phenanthrenes / isolation & purification
  • Phenanthrenes / pharmacology*
  • Phenanthrenes / toxicity
  • Tripterygium* / chemistry

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antineoplastic Agents, Alkylating
  • Antispermatogenic Agents
  • Diterpenes
  • Epoxy Compounds
  • Immunosuppressive Agents
  • Phenanthrenes
  • triptolide
  • triptophenolide