Transferrin: structure, function and potential therapeutic actions

Drug Discov Today. 2005 Feb 15;10(4):267-73. doi: 10.1016/S1359-6446(04)03333-1.

Abstract

There are many proteins that can multi-task. Transferrin, widely known as an iron-binding protein, is one such example of a multi-tasking protein. In this review, the multiple biological actions of transferrin, including its growth and cytoprotective activities, are discussed with the view of highlighting the potential therapeutic applications of this protein.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Infective Agents / therapeutic use
  • Biological Transport
  • Bone Marrow Transplantation
  • Cardiovascular Diseases / drug therapy
  • Humans
  • Iron / metabolism
  • Neoplasms / drug therapy
  • Radiotherapy
  • Receptors, Transferrin / physiology
  • Transferrin / chemistry*
  • Transferrin / physiology*
  • Transferrin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Receptors, Transferrin
  • Transferrin
  • Iron