New developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications

J Neurol. 2004 Sep:251 Suppl 6:VI/33-8. doi: 10.1007/s00415-004-1608-4.

Abstract

In this review we summarize new developments in early diagnosis, establishing surrogate markers, genetics, neuroprotection and cell replacement in Parkinson's disease. Furthermore, we discuss the major problems in the translation of results from preclinical research into successful clinical trials.

Publication types

  • Review

MeSH terms

  • Biomarkers / analysis
  • Diagnostic Imaging / methods
  • Diagnostic Imaging / trends
  • Humans
  • Nerve Growth Factors / pharmacology
  • Nerve Growth Factors / therapeutic use
  • Neuroprotective Agents / pharmacology
  • Neuroprotective Agents / therapeutic use
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / genetics
  • Parkinson Disease / therapy*
  • Stem Cell Transplantation / methods
  • Stem Cell Transplantation / trends
  • Treatment Failure

Substances

  • Biomarkers
  • Nerve Growth Factors
  • Neuroprotective Agents