Ropinirole: current status of the studies

J Neurol. 2004 Sep:251 Suppl 6:VI/13-8. doi: 10.1007/s00415-004-1604-8.

Abstract

Ropinirole is a modern, non-ergoline dopamine agonist which has been shown to be effective as monotherapy as well as combination therapy against idiopathic Parkinson's disease. In addition to improving bradykinesia, rigor and tremor, it will ameliorate the abilities of daily living as well as depressive mood. The long-term complications of L-dopa are diminished and the existing complications are reduced. A neuroprotective effect is under discussion. In addition to Parkinson's disease, ropinirole is also used successfully in the treatment of restless legs syndrome.

Publication types

  • Review

MeSH terms

  • Bromocriptine / adverse effects
  • Dopamine Agonists / pharmacology*
  • Dopamine Agonists / therapeutic use
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Humans
  • Indoles / administration & dosage*
  • Indoles / adverse effects
  • Levodopa / adverse effects
  • Neuroprotective Agents / pharmacology
  • Neuroprotective Agents / therapeutic use
  • Parkinson Disease / drug therapy*
  • Parkinson Disease / physiopathology
  • Parkinson Disease / psychology

Substances

  • Dopamine Agonists
  • Indoles
  • Neuroprotective Agents
  • ropinirole
  • Bromocriptine
  • Levodopa