Cytomegalovirus and Clostridium Difficile co-infection in severe ulcero-hemorrhagic colitis during induction chemotherapy for acute lymphoblastic leukemia

Giovanni Riva; Mario Luppi; Leonardo Potenza; Monica Morselli; Angela Ferrari; Alessia Saviola; Francesco Volzone; Annalisa Imovilli; Alberto Merighi; Antonio Maiorana; Giuseppe Torelli

Cytomegalovirus and Clostridium Difficile co-infection in severe ulcero-hemorrhagic colitis during induction chemotherapy for acute lymphoblastic leukemia

Haematologica. 2005 Jan;90(1):ECR01.

Authors

Giovanni Riva¹, Mario Luppi, Leonardo Potenza, Monica Morselli, Angela Ferrari, Alessia Saviola, Francesco Volzone, Annalisa Imovilli, Alberto Merighi, Antonio Maiorana, Giuseppe Torelli

Affiliation

¹ Department of Oncology and Hematology, University of Modena and Reggio Emilia, Italy.

PMID: 15653455

Abstract

Here we describe the first case of a biopsy-proven Cytomegalovirus ulcero-hemorrhagic colitis, associated with Clostridium Difficile co-infection, occurring during standard induction chemotherapy for common B cell acute lymphoblastic leukemia. We discuss the case and focalize clinical management and diagnostic issues arising from it.

Publication types

Case Reports

MeSH terms

Adult
Clostridioides difficile* / isolation & purification
Colitis, Ulcerative / microbiology*
Colitis, Ulcerative / pathology
Colitis, Ulcerative / virology*
Cytomegalovirus / isolation & purification
Cytomegalovirus Infections / pathology*
Enterocolitis, Pseudomembranous / pathology*
Humans
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*