Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors

Am Heart J. 2005 Jan;149(1 Suppl):S43-53. doi: 10.1016/j.ahj.2004.10.022.
No abstract available

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Angioplasty, Balloon, Coronary
  • Anticoagulants / pharmacology*
  • Anticoagulants / therapeutic use
  • Arginine / analogs & derivatives
  • Atrial Fibrillation / drug therapy
  • Azetidines / therapeutic use
  • Benzylamines
  • Clinical Trials as Topic
  • Coronary Disease / drug therapy
  • Heparin / therapeutic use
  • Hirudins / analogs & derivatives*
  • Hirudins / pharmacology
  • Humans
  • Myocardial Infarction / drug therapy
  • Peptide Fragments / therapeutic use
  • Pipecolic Acids / therapeutic use
  • Recombinant Proteins / therapeutic use
  • Sulfonamides
  • Syndrome
  • Thrombin / antagonists & inhibitors*
  • Thromboembolism / drug therapy
  • Thrombosis / drug therapy*
  • Venous Thrombosis / drug therapy

Substances

  • Anticoagulants
  • Azetidines
  • Benzylamines
  • Hirudins
  • Peptide Fragments
  • Pipecolic Acids
  • Recombinant Proteins
  • Sulfonamides
  • ximelagatran
  • Heparin
  • Arginine
  • Thrombin
  • argatroban
  • bivalirudin