The value of a general therapeutic approach in subjects with irritable bowel syndrome

Aliment Pharmacol Ther. 2005 Jan 1;21(1):21-7. doi: 10.1111/j.1365-2036.2004.02302.x.

Abstract

Background: The general therapeutic approach is the cornerstone in the management of irritable bowel syndrome, but the effect is poorly documented.

Aim: To evaluate the effect of the general therapeutic approach for irritable bowel syndrome.

Methods: Subjects with irritable bowel syndrome identified in a public screening were included. Scores for abdominal symptom (range 0-12), musculoskeletal pain and mood disorders were calculated. After exclusion of other disorders, a doctor presented irritable bowel syndrome as a positive diagnosis, gave information, reassurance and lifestyle advice, but no pharmacotherapy. A dietician gave dietary advice. There was a follow-up after 6 months.

Results: Sixty-five persons (females/males: 44/21) with mean age 49 years (range 31-76) were included, 31 (48%) were recommended dietary changes. Twenty subjects (31%) had satisfactory relief of symptoms after 6 months. The scores for abdominal symptom was reduced from 3.1 to 2.2 (P = 0.007), the reduction was 2.2 in the diarrhoea-predominant group given advice compared with 0.4 in the other subjects (P = 0.035). Previous consultations for the complaints, visits for psychiatric disorders, and presence of mood disorders were predictors of persistent complaints.

Conclusions: There was a significant relief of symptoms after 6 months, those with psychological co-morbidity responded less well. The effect of dietary advice was only seen in those with diarrhoea-predominant irritable bowel syndrome.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Diarrhea / diet therapy*
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Irritable Bowel Syndrome / diet therapy*
  • Male
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome