Abstract
Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Amphibian Proteins / chemistry*
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Amphibian Proteins / isolation & purification
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Amphibian Proteins / pharmacology
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Animals
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Anura* / metabolism
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Hemolysin Proteins / chemistry*
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Hemolysin Proteins / isolation & purification
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Hemolysin Proteins / pharmacology
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Molecular Sequence Data
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Peptides / chemistry*
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Peptides / isolation & purification
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Peptides / pharmacology
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Sequence Alignment
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Skin / chemistry
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Skin / metabolism
Substances
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Amphibian Proteins
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Hemolysin Proteins
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Peptides
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hylin b1, Hyla biobeba
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hylin b2, Hyla biobeba