Nine new metabolites, including one novel naphthoquinone derivative, chabrolonaphthoquinone A (1), four tetraprenyltoluquinol-related metabolites, chabrolohydroxybenzoquinones A-D (2-5), and four tetraprenyltoluquinone-related compounds, chabrolobenzoquinones A-D (6-9), were isolated from the organic extract of a Taiwanese soft coral, Nephthea chabrolii. The structures of 1-9 were elucidated on the basis of spectral data.