Semiconductor quantum dots and free radical induced DNA nicking

Chem Commun (Camb). 2005 Jan 7:(1):121-3. doi: 10.1039/b413175d. Epub 2004 Nov 25.

Abstract

There is a growing interest in the use of semiconductor quantum dots as fluorescent markers in biological applications. However, there are concerns regarding the potential environmental impact and toxic nature of these nanomaterials. In this study, we have investigated the interaction of water-soluble semiconductor quantum dots with supercoiled DNA.

MeSH terms

  • Biosensing Techniques*
  • Cadmium Compounds / chemistry
  • DNA, Superhelical / chemistry*
  • Fluorescence
  • Free Radicals / chemistry*
  • Nanotechnology
  • Quantum Dots*
  • Selenium Compounds / chemistry
  • Semiconductors
  • Sulfides / chemistry
  • Water / chemistry*
  • Zinc Compounds / chemistry

Substances

  • Cadmium Compounds
  • DNA, Superhelical
  • Free Radicals
  • Selenium Compounds
  • Sulfides
  • Zinc Compounds
  • Water
  • zinc sulfide