Polymyositis, invasion of non-necrotic muscle fibres, and the art of repetition

BMJ. 2004 Dec 18;329(7480):1464-7. doi: 10.1136/bmj.329.7480.1464.

Abstract

The presence of cellular inflammatory infiltrates with invasion of non-necrotic muscle fibres has become a prerequisite for the diagnosis of polymyositis, but a structured literature search shows that the research evidence is insufficiently strong for this histological feature to be used as a diagnostic criterion

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Muscle Fibers, Skeletal / pathology*
  • Muscular Diseases / pathology*
  • Necrosis
  • Polymyositis / pathology*