Abstract
The case of a 61-years-old female patient with chronic hepatitis C who developed multiple consecutive extrahepatic manifestations is reported. One of these manifestations (lichen planus) appeared before HCV-related chronic hepatitis was diagnosed and treated with interferon-alpha, suggesting that it was likely associated with HCV itself. Other manifestations appeared during IFN-alpha treatment (polyarthritis) or after the end of treatment (ulcerative cholitis, sarcoidosis) implying a role for either HCV or IFN-alpha treatment in the pathogenesis of extrahepatic manifestations.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Anti-Inflammatory Agents / therapeutic use
-
Antiviral Agents / adverse effects*
-
Antiviral Agents / therapeutic use*
-
Arthritis / chemically induced
-
Arthritis / etiology*
-
Colitis, Ulcerative / chemically induced
-
Colitis, Ulcerative / diagnosis
-
Colitis, Ulcerative / etiology*
-
Female
-
Hepatitis C, Chronic / complications*
-
Hepatitis C, Chronic / diagnosis
-
Hepatitis C, Chronic / drug therapy*
-
Humans
-
Interferon-alpha / adverse effects*
-
Interferon-alpha / therapeutic use*
-
Lichen Planus / diagnosis
-
Lichen Planus / etiology*
-
Middle Aged
-
Prednisone / therapeutic use
-
Sarcoidosis, Pulmonary / chemically induced
-
Sarcoidosis, Pulmonary / diagnosis
-
Sarcoidosis, Pulmonary / drug therapy
-
Sarcoidosis, Pulmonary / etiology*
-
Time Factors
Substances
-
Anti-Inflammatory Agents
-
Antiviral Agents
-
Interferon-alpha
-
Prednisone