Metronomic scheduling of trofosfamide chemotherapy in human NSCLC xenografts highly increases therapeutic efficacy compared to conventional scheduling by inhibition of angiogenesis

MeSH terms

• Animals
• Antineoplastic Agents, Alkylating / administration & dosage
• Antineoplastic Agents, Alkylating / therapeutic use*
• Carcinoma, Non-Small-Cell Lung / drug therapy*
• Cyclophosphamide / administration & dosage
• Cyclophosphamide / analogs & derivatives*
• Cyclophosphamide / therapeutic use*
• Drug Administration Schedule
• Humans
• Lung Neoplasms / drug therapy*
• Mice
• Mice, Nude
• Neovascularization, Pathologic / prevention & control*
• Transplantation, Heterologous
• Tumor Cells, Cultured