Abstract
Two new sesquiterpenes, godotol A (1) and godotol B (2), were isolated from Pluchea arabica. Their structures were determined by analysis of NMR data. The absolute configurations of 1 and 2 were established by Mosher ester methodology. The godotols displayed weak activity against bacteria and the brine shrimp larvae. They were also inactive in the DPPH antioxidant assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Artemia / drug effects
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Asteraceae / chemistry*
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Biphenyl Compounds
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Candida albicans / drug effects
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Escherichia coli / drug effects
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Klebsiella pneumoniae / drug effects
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Microbial Sensitivity Tests
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Oman
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Picrates / pharmacology
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Plants, Medicinal / chemistry*
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Pseudomonas aeruginosa / drug effects
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Salmonella arizonae / drug effects
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes / pharmacology
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Staphylococcus aureus / drug effects
Substances
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Biphenyl Compounds
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Picrates
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Sesquiterpenes
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godotol A
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godotol B
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1,1-diphenyl-2-picrylhydrazyl