New sesquiterpenes from Capsicum annuum

J Nat Prod. 2004 Nov;67(11):1893-6. doi: 10.1021/np0305472.

Abstract

The ethyl acetate soluble fraction of a MeOH extract of the dried stems and roots of Capsicum annum gave 10 new sesquiterpenoids (1-10) and nine known compounds. The structures of the new compounds were elucidated on the basis of spectroscopic evidence. The isolated new compounds were evaluated for their cytotoxic activities.

MeSH terms

  • Capsicum / chemistry*
  • Crystallography, X-Ray
  • HIV / drug effects
  • Humans
  • Japan
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology
  • Tumor Cells, Cultured / drug effects

Substances

  • Sesquiterpenes