Objective: To investigate the clinical efficacy and safety of photon therapy for benign prostate hyperplasia (BPH).
Methods: Thirty patients with severe BPH received brachytherapy of prostate photon treatment system irradiation for one month, with the active area of the applicator located in the rectum, and at a dosage of 726-810 cGy. International prostate symptom score (IPSS), quality of life (QOL), volume of prostate gland, maximum flow rate (Qmax), and residual urine were evaluated before and after the treatment.
Results: After one-month treatment, 18 cases remarkably improved, 9 slightly improved and 3 had no response. There was significant improvement in IPSS, QOL, volume of prostate gland, Qmax and residual urine (P<0.01, except Qmax P = 0.038).
Conclusion: Prostate photon treatment system can be used as a safe, effective, micro-invasive, convenient and economical therapy for severe BPH, especially applicable to older and weaker patients.