Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases

Alessandra Micera; Alessandro Lambiase; Luigi Aloe; Sergio Bonini; Francesca Levi-Schaffer; Stefano Bonini

doi:10.1016/j.cytogfr.2004.09.003

Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases

Cytokine Growth Factor Rev. 2004 Dec;15(6):411-7. doi: 10.1016/j.cytogfr.2004.09.003.

Authors

Alessandra Micera¹, Alessandro Lambiase, Luigi Aloe, Sergio Bonini, Francesca Levi-Schaffer, Stefano Bonini

Affiliation

¹ CIR Laboratorio di Oftalmologia, Campus Bio-Medico and Fondazione GB Bietti, Rome, Italy.

PMID: 15561599
DOI: 10.1016/j.cytogfr.2004.09.003

Abstract

The purpose of this review is to outline the main role of nerve growth factor (NGF) in the visual system and particularly in the ocular surface in physiological and pathological conditions. The present review of experimental and clinical studies will highlight old and recent strategies for treating ocular surface and tear disorders with NGF.

Publication types

Review

MeSH terms

Eye Diseases* / immunology
Eye Diseases* / pathology
Eye Diseases* / physiopathology
Humans
Hypersensitivity / pathology
Hypersensitivity / physiopathology*
Nerve Growth Factor / metabolism*
Neurodegenerative Diseases / pathology
Neurodegenerative Diseases / physiopathology*
Ocular Physiological Phenomena
Receptor, Nerve Growth Factor
Receptor, trkA / metabolism
Receptors, Nerve Growth Factor / metabolism

Substances

Receptor, Nerve Growth Factor
Receptors, Nerve Growth Factor
Nerve Growth Factor
Receptor, trkA