[A case of long-term survivor with multiple pulmonary metastases of HCC after hepatic resection]

Gan To Kagaku Ryoho. 2004 Oct;31(11):1939-42.
[Article in Japanese]

Abstract

A 52-year-old male was admitted to our hospital with huge hepatoma of the right lobe. He underwent a right lobectomy of the liver in July 1999. After five months from the surgery, multiple recurrences in the liver and lung were revealed with Computed tomography (CT). TAE was performed for intrahepatic recurrence and a combination therapy, consisting of UFT and interferon-alpha, was started for pulmonary metastasis. Then 5-FU/CDDP/interferon-alpha therapy was given in 2001 and TS-1/interferon-beta therapy was given thereafter in 2002. Consequently, the patient survived for 31 months with no disturbance in quality of life. No intrahepatic recurrence was also detected during the survival period. It was suggested that a good prognosis may be expected, even in the HCC case with distant metastasis after hepatic resection, if the primary cite was curatively treated.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Hepatocellular / pathology*
  • Carcinoma, Hepatocellular / surgery
  • Cisplatin / administration & dosage
  • Drug Combinations
  • Fluorouracil / administration & dosage
  • Hepatectomy*
  • Humans
  • Interferon-alpha / administration & dosage
  • Interferon-beta / administration & dosage
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / surgery
  • Lung Neoplasms / mortality
  • Lung Neoplasms / secondary*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Oxonic Acid / administration & dosage
  • Pyridines / administration & dosage
  • Tegafur / administration & dosage
  • Tegafur / therapeutic use
  • Time Factors
  • Uracil / therapeutic use

Substances

  • Drug Combinations
  • Interferon-alpha
  • Pyridines
  • S 1 (combination)
  • Tegafur
  • Uracil
  • Oxonic Acid
  • Interferon-beta
  • Cisplatin
  • Fluorouracil

Supplementary concepts

  • 1-UFT protocol