Expression of tocopherol-associated protein in mast cells

Clin Diagn Lab Immunol. 2004 Nov;11(6):1189-91. doi: 10.1128/CDLI.11.6.1189-1191.2004.

Abstract

Tocopherol-associated protein (TAP) was expressed in mouse mast cells. TAP was predominantly localized in the cytoplasm, and the subcellular localization was not changed by alpha-tocopherol. The results suggest that the physiological role of TAP in mast cells is not regulation of tocopherol function but an as-yet-unidentified activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Carrier Proteins / metabolism*
  • Cells, Cultured
  • Lipoproteins / metabolism*
  • Mast Cells / metabolism*
  • Mice
  • Protein Transport / drug effects
  • Trans-Activators / metabolism*
  • alpha-Tocopherol / pharmacology*

Substances

  • Antioxidants
  • Carrier Proteins
  • Lipoproteins
  • Trans-Activators
  • tocopherol-associated protein, mouse
  • alpha-Tocopherol