Dystonia in a 13-year-old boy with secondary progressive multiple sclerosis

Brain Dev. 2004 Dec;26(8):539-41. doi: 10.1016/j.braindev.2004.02.014.

Abstract

We report a patient who developed relapsing-remitting multiple sclerosis (MS) at 8 years old, and then had a progressive clinical course and dystonia. Dystonia of the patient is probably due to a lesion of the basal ganglia. Abnormal posture or movement disorder is very rarely found in MS, and progressive clinical course is also rare in childhood. The patient is worthy of attention because of his childhood onset, progressive clinical course and dystonia.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age Factors
  • Age of Onset
  • Arm / pathology
  • Arm / physiopathology
  • Basal Ganglia / pathology
  • Basal Ganglia / physiopathology*
  • Basal Ganglia Diseases / etiology*
  • Basal Ganglia Diseases / pathology
  • Basal Ganglia Diseases / physiopathology
  • Disease Progression
  • Dystonia / etiology*
  • Dystonia / pathology
  • Dystonia / physiopathology
  • Electromyography
  • Humans
  • Interferon beta-1b
  • Interferon-beta / therapeutic use
  • Leg / pathology
  • Leg / physiopathology
  • Male
  • Multiple Sclerosis, Chronic Progressive / complications*
  • Multiple Sclerosis, Chronic Progressive / pathology
  • Multiple Sclerosis, Chronic Progressive / physiopathology
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiopathology
  • Muscular Atrophy / etiology
  • Muscular Atrophy / pathology
  • Muscular Atrophy / physiopathology
  • Treatment Outcome

Substances

  • Interferon beta-1b
  • Interferon-beta