Abstract
Mating-type switching in fission yeast has long been known to be directed by a DNA 'imprint'. This imprint has now been firmly characterized as a protected site-specific and strand-specific nick. New work also links the widely conserved Swi1-Swi3 complex to the protection of stalled replication forks in general.
MeSH terms
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Cell Cycle Proteins
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Chromosomal Proteins, Non-Histone
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DNA Replication / physiology*
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DNA-Binding Proteins
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Genes, Fungal / genetics*
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Genes, Mating Type, Fungal*
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Models, Genetic*
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Nuclear Proteins / genetics
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Saccharomyces cerevisiae / genetics*
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Saccharomyces cerevisiae Proteins / genetics
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Schizosaccharomyces / genetics*
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Schizosaccharomyces pombe Proteins
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Trans-Activators / genetics
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Transcription Factors / genetics
Substances
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Cell Cycle Proteins
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Chromosomal Proteins, Non-Histone
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DNA-Binding Proteins
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Nuclear Proteins
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SWI1 protein, S cerevisiae
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SWI3 protein, S cerevisiae
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Saccharomyces cerevisiae Proteins
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Schizosaccharomyces pombe Proteins
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Trans-Activators
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Transcription Factors
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swi1 protein, S pombe