Smoothing of the ablated porcine anterior corneal surface using the Technolas Keracor 217C and Nidek EC-5000 excimer lasers

J Refract Surg. 2004 Sep-Oct;20(5):450-3. doi: 10.3928/1081-597X-20040901-07.

Abstract

Purpose: To demonstrate efficacy of a smoothing technique to increase regularity of the anterior corneal surface after photorefractive keratectomy (PRK), using two different excimer lasers.

Methods: Spherical ablations of -10.00 D were performed on 11 fresh porcine corneas using either the Technolas Keracor 217C scanning-spot or the Nidek EC-5000 scanning-slit beam excimer laser. Following the procedure, we performed a phototherapeutic keratectomy treatment (smoothing technique) on half of the corneal surface. The smoothing technique was performed using a viscous solution of 0.25% sodium hyaluronate, which was spread on the cornea prior to the procedure. The ablation zone was 6 mm in diameter and the transition zone extended to 3 mm. The ablation depth was set at 10 microm. Corneas were then examined with scanning electron microscopy.

Results: Smoother treatment zones were apparent in porcine corneas in which smoothing was performed following PRK, with both laser systems. Results from the two lasers were not directly compared.

Conclusions: The smoothing procedure performed following PRK using a viscous 0.25% sodium hyaluronate masking solution and a scanning laser system rendered the porcine corneal surface more regular.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cornea / surgery*
  • Cornea / ultrastructure
  • Equipment Design
  • Hyaluronic Acid / chemistry
  • Hyaluronic Acid / pharmacology
  • Image Processing, Computer-Assisted
  • In Vitro Techniques
  • Lasers*
  • Lasers, Excimer
  • Microscopy, Electron, Scanning
  • Photorefractive Keratectomy / instrumentation
  • Photorefractive Keratectomy / methods*
  • Solutions
  • Swine
  • Viscosity

Substances

  • Solutions
  • Hyaluronic Acid