[Features of the treatment of heart failure in the elderly]

Presse Med. 2004 Sep 25;33(16):1086-8. doi: 10.1016/s0755-4982(04)98853-7.
[Article in French]

Abstract

PHARMACOLOGICAL MODIFICATIONS TO BE TAKEN INTO ACCOUNT: In elderly patients, there is a modification in the distribution columns of drugs, an alteration in glomerular filtration (doses require adaptation) and tubular function (greater sensitivity to low salt diet and diuretics), and a reduction in the hepatic elimination capacity. FOR SYSTOLIC HEART FAILURE: The choice of drugs is in practice the same as that for younger patients: diuretics, antialdosterone agents, converting enzyme inhibitors, angiotensin II receptor antagonists, beta-blockers and digitalics. FOR DIASTOLIC HEART FAILURE: The therapeutic approach combines an etiologic treatment (blood pressure, myocardial ischaemia), prevention and the rapid treatment of the decompensation factors (atrial arrhythmia), a pharmacological treatment (converting enzyme inhibitors, angiotensin II receptor antagonists, and bradycardia lowering agents). Non-pharmacological measures include dietary restrictions, regular physical exercise, and education for the patient and the family.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Aging*
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Diet
  • Diuretics / therapeutic use
  • Exercise Therapy
  • Glomerular Filtration Rate
  • Heart Failure / drug therapy*
  • Heart Failure / pathology
  • Humans
  • Hypertension / complications
  • Liver / physiology
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Myocardial Ischemia / complications
  • Risk Factors

Substances

  • Adrenergic beta-Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Diuretics
  • Mineralocorticoid Receptor Antagonists