Abstract
The prevalence of extended-spectrum beta-lactamases (ESBL)-producing organisms in an urban hospital in Dhaka City was assessed over a 10-month period. A double disk test was performed to detect ESBL-producing Escherichia coli and Klebsiella pneumoniae. 43.2% and 39.5% of E. coli and K. pneumoniae had ESBL phenotypes, respectively. The combination of augmentin with ceftazidime detected the most ESBL-producing E. coli (39.5%) while augmentin with ceftriaxone was the best combination for the detection of ESBL (31.6%) in K. pneumoniae.
MeSH terms
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Amoxicillin-Potassium Clavulanate Combination / pharmacology
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Bangladesh / epidemiology
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Ceftazidime / pharmacology
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Ceftriaxone / pharmacology
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Escherichia coli / drug effects
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Escherichia coli / enzymology*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Female
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Hospitals, Urban
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Humans
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Klebsiella / drug effects
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Klebsiella / enzymology*
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Klebsiella / genetics
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Klebsiella / isolation & purification
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Male
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Microbial Sensitivity Tests
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Prevalence
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beta-Lactam Resistance
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beta-Lactamases / genetics
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beta-Lactamases / metabolism*
Substances
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Amoxicillin-Potassium Clavulanate Combination
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Ceftriaxone
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Ceftazidime
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beta-Lactamases