[Obstructive sleep apnea syndrome as a risk factor of glaucomatous neuropathy]

Klin Oczna. 2004;106(1-2 Suppl):245-6.
[Article in Polish]

Abstract

The consequences of sleep apneas in patients with obstructive sleep apnea (OSA) syndrome may influence the function of visual system. In 21 patients with OSA syndrome (apnea/hypopnea index--AHI 50+/-20) the detailed ophthalmologic studies, including tonometry, biomicroscopic evaluation of the anterior segment of the eye, automatic perimetry and stereoscopic examination of the eye fundus have been performed. In 4 patients (19%) the signs of lesions in the optic tract have been found. These were: defects in visual field caused by glaucoma (primary open-angle glaucoma and normal-tension glaucoma) in 2 patients and defects in visual field (concentric and quadrantic homonymous) caused by diffuse lesions in the cortico-nuclear tract in 2 patients. In patients with the lesions in the optic tract there were severe disorders of breathing during sleep: AHI >60, mean SaO2 at the end of the apneas <86% and minimal SaO2 at the end of the apneas <70%. The authors conclude that in OSA patients there is a high risk of the lesions of the optic tract as a consequence of severe and repetitive hypoxemia during sleep.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Female
  • Glaucoma / complications*
  • Glaucoma / pathology
  • Glaucoma / physiopathology
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Ophthalmoscopy
  • Optic Nerve / pathology*
  • Optic Nerve / physiopathology
  • Optic Nerve Diseases / etiology*
  • Optic Nerve Diseases / pathology
  • Optic Nerve Diseases / physiopathology
  • Sleep Apnea, Obstructive / complications*
  • Tonometry, Ocular
  • Visual Field Tests
  • Visual Fields