Allylsilanes and vinylsilanes from silylcupration of carbon-carbon multiple bonds: scope and synthetic applications

Asunción Barbero; Francisco J Pulido

doi:10.1021/ar0400490

Allylsilanes and vinylsilanes from silylcupration of carbon-carbon multiple bonds: scope and synthetic applications

Acc Chem Res. 2004 Oct;37(10):817-25. doi: 10.1021/ar0400490.

Authors

Asunción Barbero¹, Francisco J Pulido

Affiliation

¹ Departamento de Química Orgánica, Facultad de Ciencias, C/ Dr Mergelina s/n, 47011 Valladolid, Spain.

PMID: 15491128
DOI: 10.1021/ar0400490

Abstract

Silylcupration of multiple bonds (allenes, acetylenes, dienes, and styrenes) has become one of the most efficient procedures for the synthesis of vinyl- and allylsilanes. These substrates are useful building blocks in organic synthesis since they undergo a great variety of silicon-assisted transformations. The methodology reported has been widely used in the synthesis of different natural products, as well as in the construction of carbo- and heterocycles. In this Account, we wish to illustrate our contribution to this field, as well as to highlight the contributions of others.