Abstract
Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Animals
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Antibodies, Helminth / immunology
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Antigens, Helminth / blood*
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Biomarkers / blood
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Chronic Disease
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Enzyme-Linked Immunosorbent Assay
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Helminth Proteins / blood*
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Hemocyanins / analysis
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Hemocyanins / immunology*
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Humans
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Immunoglobulin G / blood
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Immunoglobulin M / blood
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Schistosoma mansoni / immunology*
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Schistosomiasis mansoni / blood
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Schistosomiasis mansoni / diagnosis*
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Sensitivity and Specificity
Substances
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Antibodies, Helminth
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Antigens, Helminth
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Biomarkers
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Helminth Proteins
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Immunoglobulin G
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Immunoglobulin M
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p40 egg antigen, Schistosoma
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Hemocyanins
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keyhole-limpet hemocyanin