Predicted value of renin activity in a woman who had severe ovarian hyperstimulation syndrome with internal jugular vein thrombosis

Fertil Steril. 2004 Oct;82(4):937-9. doi: 10.1016/j.fertnstert.2004.02.142.

Abstract

Objective: To assess plasma renin activity in a patient with severe ovarian hyperstimulation syndrome (OHSS) and internal jugular vein thrombosis.

Design: Case report.

Setting: University-affiliated infertility center.

Patient(s): A 33-year-old woman with OHSS and internal jugular vein thrombosis.

Intervention(s): Controlled ovulation hyperstimulation with recombinant FSH induction.

Main outcome measure(s): Plasma renin activity (PRA), color Doppler ultrasound of the neck.

Result(s): The patient had internal jugular vein thrombosis caused by severe OHSS. The PRA was significantly elevated during the acute stage and subsequently declined after resolution of the OHSS.

Conclusion(s): In this patient elevated PRA appeared to be associated with the development of OHSS and thrombosis. The implication of the ovarian renin-angiotensin system in the development of OHSS and thrombosis is relevant.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Therapeutic
  • Adult
  • Anticoagulants / therapeutic use
  • Embryo Transfer
  • Female
  • Fertilization in Vitro
  • Humans
  • Jugular Veins*
  • Male
  • Ovarian Hyperstimulation Syndrome / blood*
  • Ovarian Hyperstimulation Syndrome / complications
  • Ovarian Hyperstimulation Syndrome / therapy
  • Pregnancy
  • Renin / blood*
  • Superovulation
  • Venous Thrombosis / blood*
  • Venous Thrombosis / complications
  • Venous Thrombosis / therapy

Substances

  • Anticoagulants
  • Renin